University of Edinburgh Featured PhD Programmes
University of Leeds Featured PhD Programmes
University of Glasgow Featured PhD Programmes

Investigating the role of the FGF pathway in gene regulation during early amphibian development.

Department of Biology

This project is no longer listed on and may not be available.

Click here to search for PhD studentship opportunities
Dr H V Isaacs , Dr M E Pownall No more applications being accepted Self-Funded PhD Students Only

About the Project

The Fibroblast Growth Factor (FGF) signalling pathway plays critical roles in regulating cell lineage during normal development and stem cell differentiation in culture. FGF signalling is also important in adult homeostasis and is often misregulated during the development of cancer. We have a good understanding of the developmental processes and target genes regulated by FGF signalling during early amphibian development. However, several different members of the FGF family of ligands and receptors are expressed in early development and, at present, it is not clear what role each individual FGF or FGF receptor has in mediating the effects of FGF signalling. We will use Cas9/CRISPR mediated gene editing to investigate the developmental effects of inhibiting individual FGF ligands and receptors. The project will provide excellent training in the research process and the candidate will gain experience in a wide range of embryological and molecular biological approaches to investigating gene expression and function in early development.

Funding Notes

This is a self-funded project. Applicants need to have adequate funds to meet the costs of a self-funded research project including tuition fees and living expenses for the duration of the research programme. Please see information on tuition fee costs, living expenses and funding opportunities.


Applications are welcome for a 1-year MSc by Research.
Search Suggestions

Search Suggestions

Based on your current searches we recommend the following search filters.

FindAPhD. Copyright 2005-2021
All rights reserved.