Continue with FacebookLooking to list your PhD opportunities? Log in here.
Dr James Burrows
Applications accepted all year round
Competition Funded PhD Project (UK Students Only)
Belfast
United Kingdom
Biochemistry
Cancer Biology
Cell Biology
Molecular Biology
Biological Sciences
Medicine
Pharmacology
Pharmacy
About the Project
USP17 is over-expressed in a range of primary tumours (NSCLC, breast, colorectal, cervical, ovarian, osteosarcoma) and its depletion blocks the growth, and migration, of cells from all of these cancer types. As a result, USP17 represents a potential therapeutic target in these cancers.
Our lab has been working to explore the physiological function of USP17 to help us understand why it is important in these cancers, and how targeting this deubiquitinase will impact upon cancer and normal cells. We, and others, have shown that USP17 can impact upon molecules involved in epithelial to mesenchymal transition (EMT), a cellular program that can contribute to cancer progression, as well as to normal functions such as wound repair. Therefore, in this project we will further investigate the regulation of EMT by USP17 in both normal and cancer cells, to determine what this tells us about the normal function of USP17, and how this might contribute to cancer progression.
The student will be part of a cross-disciplinary team based in the School of Pharmacy with Dr Burrows. The student will have the opportunity to learn a broad range of molecular and cell biology techniques. This project will also allow the student to gain skills in written and verbal scientific presentation skills.
The student will have the opportunity to learn a range of molecular biology, protein biochemistry and cell biology related techniques as well as developing transferable skills such as written and verbal scientific presentation skills.
Home applicants must meet the following academic criteria:
1st or 2.1 honours degree in a relevant subject. Relevant subjects include Pharmacy, Pharmaceutical Sciences, Biochemistry, Biological/Biomedical Sciences, Chemistry, Engineering, or a closely related discipline.
International applicants must meet the following academic criteria:
IELTS (or equivalent) of 7.0, a 2.1 honours degree (or equivalent) and a master’s degree in a relevant subject.
Funding Notes
Department for the Economy studentships are open for applications to Home and International applicants for October 2023 entry. Eligibility and funding information is available here: View Website
Email Now
You haven’t included a message. Providing a specific message means universities will take your enquiry more seriously and helps them provide the information you need.
Why not add a message here
Why not add a message here
* required field
The information you submit to Queen’s University Belfast will only be used by them or their data partners to deal with your enquiry, according to their privacy notice. For more information on how we use and store your data, please read our privacy statement.
Search suggestions
Based on your current searches we recommend the following search filters.
Check out our other PhDs in Belfast, United Kingdom
Check out our other PhDs in United Kingdom
Start a New search with our database of over 4,000 PhDs
PhD suggestions
Based on your current search criteria we thought you might be interested in these.
Investigating the role of bioactive lipids in skin health
The University of Manchester
Investigating the role of the biofilm in waste water treatment plants as a reservoir for antimicrobial resistance
Glasgow Caledonian University
Investigating the role of food as a vehicle for microbial transmission and antimicrobial resistance genes.
Glasgow Caledonian University