Circularly polarized luminescence (CPL) of lanthanides is sensitive to the local molecular environment, which can be used in biomolecular science. So far, however, only a few CPL applications in DNA studies have been reported. We will try to overcome some restraints of the methodology, such as by using a Raman optical activity (ROA) spectrometer to measure CPL spectra. This will make it possible to use lanthanide aqua-ions as non-invasive DNA probes in concentrations not distorting DNA structure. We expect to establish a connection between CPL and ROA spectral features and specifics of DNA structures.
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To apply for a PhD study at IOCB Prague, you must hold a Master’s degree (MSc) or the equivalent of the MSc in similar field (four or five year undergraduate degree). The application can be submitted before obtaining the Master’s degree, however, the applicant should obtain the degree within five months after the application deadline.
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Keiderling, T. A.; Bouř, P. Phys. Rev. Lett. 2018, 121, 073201. “Theory of Molecular Vibrational Zeeman Effects as Measured with Circular Dichroism.”
Hudecová, J.; Profant, V.; Novotná, P.; Baumruk, V.; Urbanová, M.; Bouř, P. J. Chem. Theory Comput. 2013, 9, 3096−3108. “CH Stretching Region: Computational Modeling of Vibrational Optical Activity.”