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  Light bulb moments in the mind’s eye: take a closer look


   Centre for Clinical Brain Sciences

This project is no longer listed on FindAPhD.com and may not be available.

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  Prof Baljean Dhillon, Prof Ian Underwood  No more applications being accepted  Funded PhD Project (UK Students Only)

About the Project

The Advanced Care Research Centre (ACRC) is a new, multi-disciplinary, £20M research centre at the University of Edinburgh. The ACRC will lead society’s response to the grand challenge of an ageing population that is growing in size, longevity and needs through the pursuit of research intended to deliver “high‐quality data‐driven, personalised and affordable care to support the independence, dignity and quality‐of‐life of people living in their own homes and in supported care environments”.

This project sits within the ACRC Academy , a dedicated Centre for Doctoral Training, co-located with the ACRC, whose students will deliver key aspects of the ACRC research agenda through a new doctoral-level research and training programme that will also equip them for careers across a wide range of pioneering and influential leadership roles in the public, private and third sectors.

The PhD with Integrated Study in Advanced Care is a novel, structured, thematic, cohort-based, programme of 48 months duration. Each PhD research project within the Academy has been devised by a supervisory team comprising academic staff from at least two of the three colleges within the University of Edinburgh. Each annual cohort of around twelve will include students with disciplinary backgrounds spanning from engineering and data science to humanities, social science, business and commerce, social work, medicine and related health and care professions. This unique level of diversity is a key attribute of our programme.

 

Project

Vision is our primary sense and a key determinant of independent function and life quality. A major proportion of brain function is devoted to visual processing allowing us to make sense of the world. Vision in general, and reading in particular sits at the heart of physical and emotional wellbeing for many people, from books to medicine bottles and communication with the outside world by email or text. Reading assumes especial importance in the context of frailty and poor mobility of older age, as highlighted in the current covid19 era forcing many elderly individuals to remain isolated indoors.

Increased lighting is required for reading and safe navigation as we age, more so for those affected by chronic eye diseases most commonly age-related macular degeneration (AMD). There is increasing reliance on backlit electronic devices and high output LEDs to enable reading. An undesirable consequence of excessive light exposure, especially shorter wavelength blue later in the day, is disruption to circadian rhythms mediated through neural connections between the eyes and brain. This impacts all aspects of physiology and health including sleep quality and cognitive functioning.

Following several of our recent successful PhDs, the use of head-mounted displays to aid reading in macular disease, the photobiology of blue light interactions with the retina and LED models of AMD, the purpose of this PhD project is to examine screen-based technologies to enhance reading performance, general health and quality of life of older people in their home environment. The successful student will investigate the interface between the benefit of screen-based technology and risk of intolerance in using increased ambient luminance for reading, and explore novel ways to remotely monitor the interaction in this clinically relevant project which usefully translates to patient care in the community.

Eligibility:

We are specifically looking for applicants who will view their cutting-edge PhD research project in the context of the overall vision of the ACRC, who are keen to contribute to tackling a societal grand challenge and who can add unique value to – and derive great benefit from – training in a cohort comprising colleagues with a very diverse range of disciplines and backgrounds. We advise prospective candidates to engage in dialogue with the named project supervisor and/or the Director of the Academy prior to submitting an application.

Biological Sciences (4) Computer Science (8) Engineering (12) Mathematics (25) Medicine (26) Physics (29)

Funding Notes

PhDs are funded with an enhanced stipend for the full 4 year period.

Application forms are now available here:
https://forms.office.com/Pages/ResponsePage.aspx?id=sAafLmkWiUWHiRCgaTTcYTowdNhupkBEnjWtstgAk6lURUU1SEVWUDJSM0s4RVVOSEQySU5LVEtOMS4u

Find more information on how to apply on the How to Apply section of our website:
https://www.ed.ac.uk/usher/advanced-care-research-centre/academy/how-to-apply

References

Video PhD Introduction


ACRC Academy Video:



The Scottish Collaborative Optometry-Ophthalmology Network e-research (SCONe)
Prof B Dhillion
Prof I Underwood


Dynamic text presentation on smart glasses: A pilot evaluation in age-related macular degeneration
Moshtael H, Underwood I, Nuthmann A, Underwood I, Dhillon B
British Journal of Visual Impairment 2020, Vol. 38(1) 24–37
Blue-light induced breakdown of barrier function on human retinal epithelial cells is mediated by PKC-zeta over-activation and oxidative stress.
Ozkaya EK, Anderson G, Dhillon B, Bagnaninchi PO.Exp Eye Res. 2019 Dec;189:107817. doi: 10.1016/j.exer.2019.107817. Epub 2019 Sep 26
High Tech Aids Low Vision: A Review of Image Processing for the Visually Impaired.
Moshtael H, Aslam T, Underwood I and Dhillon B.Transl Vis Sci Technol. 2015 Aug 14;4(4):6. doi: 10.1167/tvst.4.4.6. eCollection 2015 Aug
New light for old eyes: comparing melanopsin-mediated non-visual benefits of blue-light and UV-blocking intraocular lenses.
Schmoll C, Khan A, Aspinall P, Goudie C, Koay P, Tendo C, Cameron J, Roe J, Deary I and Dhillon B. Br J Ophthalmol. 2014 Jan;98(1):124-8. doi: 10.1136/bjophthalmol-2013-304024. Epub 2013 Oct 24
Reaction time as a measure of enhanced blue-light mediated cognitive function following cataract surgery.
Schmoll C, Tendo C, Aspinall P and Dhillon B. Br J Ophthalmol. 2011 Dec;95(12):1656-9. doi: 10.1136/bjophthalmol-2011-300677. Epub 2011 Sep 27
The role of retinal regulation of sleep in health and disease.
Schmoll C, Lascaratos G, Dhillon B, Skene D, Riha RL.Sleep Med Rev. 2011 Apr;15(2):107-13. doi: 10.1016/j.smrv.2010.06.001. Epub 2010 Oct 30

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