About the Project
We have identified candidate long-noncoding RNAs (lncRNAs) that might act as novel regulators of the crosstalk of BCR signaling/T-cell interactions/adhesion in B cell malignancies. This will be further investigated by the PhD student using technics such as genome editing (CRISPRi), RNA sequencing, functional studies with various in vitro (primary cells and cell lines), and in vivo models. The research is also relevant for pre-clinical development of novel RNA-based therapeutic trials, and resistance mechanisms to BCR inhibitors.
WHAT DO WE OFFER:
• modern laboratories, project funded by the prestigious ERC grant = high risk and high gain, state-of-the-art instrument, stable funding, competitive scholarship
• You will work in a team of young investigators that challenge some long standing problems in the field of hematology. We do basic science, but with the objective to help patients in the future (we have access to primary samples with hem. malignancies, and we suggest novel clinical trials).
Why not add a message here
Based on your current searches we recommend the following search filters.
Based on your current search criteria we thought you might be interested in these.