About the Project
We will determine:
Objective 1. How does transcription of Hox lncRNAs regulate Hox gene expression?
Objective 2. How is transcription through Hox regulatory elements communicated between the two chromosomes?
Objective 3. What are the lncRNA associated protein components involved in Hox transcriptional regulation?
Candidates are expected to hold (or be about to obtain) a minimum upper second class honours degree (or equivalent) in a related area/subject. Candidates with experience in Developmental Biology and Genetics or with an interest in noncoding RNA and Hox gene function and evolution are encouraged to apply.
For information on how to apply for this project, please visit the Faculty of Biology, Medicine and Health Doctoral Academy website (https://www.bmh.manchester.ac.uk/study/research/apply/). Informal enquiries may be made directly to the primary supervisor. On the online application form select PhD Developmental Biology.
For international students, we also offer a unique 4 year PhD programme that gives you the opportunity to undertake an accredited Teaching Certificate whilst carrying out an independent research project across a range of biological, medical and health sciences. For more information please visit http://www.internationalphd.manchester.ac.uk
Equality, diversity and inclusion is fundamental to the success of The University of Manchester and is at the heart of all of our activities. The full Equality, diversity and inclusion statement can be found on the website View Website
M Ronshaugen, M Levine. Developmental cell 7 (6), 925-932.
smiFISH and embryo segmentation for single-cell multi-gene RNA quantification in arthropods (2020)
L Calvo, M Ronshaugen, T Pettini. bioRxiv.
Transvection and pairing of a Drosophila Hox long noncoding RNA in the regulation of Sex combs reduced
T Pettini, MR Ronshaugen (2016) bioRxiv, 045617
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