European Molecular Biology Laboratory (Heidelberg) Featured PhD Programmes
King’s College London Featured PhD Programmes
Brunel University London Featured PhD Programmes
Engineering and Physical Sciences Research Council Featured PhD Programmes
University of Sheffield Featured PhD Programmes

Magnetic-silk Core-shell Nanoparticles for Targeted Drug and Gene Delivery

  • Full or part time
  • Application Deadline
    Applications accepted all year round
  • Self-Funded PhD Students Only
    Self-Funded PhD Students Only

Project Description

Silk is a protein fibre produced by silkworm. It has been used for centuries because of its unique properties. Extensive research has been carried out to explore the regenerated silk fibroin (RSF) as biomaterials such as tissue culture scaffolds, wound covering materials, soft contact lens, and cosmetic components for their impressive biocompatibility and biodegradability.

This PhD project is to engineer smart RSF nanocarriers with magnetic nanoparticles inside for drug and gene delivery. The student will be lab based and will be trained to use modern techniques such as AFM, SEM, TEM, FTIR, Dynamic Light Scattering (DLS), Circular Dichroism Spectroscopy (CD), Flow Cytometry, Confocal Laser Scanning Microscopy (CLSM) etc. to fabricate the nanoparticles and characterize their properties. Antibody will be conjugated onto the nanoparticles for cell targeting. A combination of relevant cell assays will also be carried out to evaluate the biocompatibility, degradability and biological functions of the fabricated nanoparticles.

Funding Notes

Applicants should have or expect to gain a first class or upper second-class honours degree (or equivalent if from overseas) in any of the following backgrounds: chemistry, physics, biochemistry, biotechnology, biomaterials, biomedical engineering, pharmaceutics, bioengineering, chemical engineering or a related discipline, or have an appropriate MSc qualification.

If English is not your first language then you must have International English Language Testing Service (IELTS) certificate with an average of 6.5 or above and at least 6.0 in each component.

Email Now

Insert previous message below for editing? 
You haven’t included a message. Providing a specific message means universities will take your enquiry more seriously and helps them provide the information you need.
Why not add a message here
* required field
Send a copy to me for my own records.

Your enquiry has been emailed successfully





FindAPhD. Copyright 2005-2019
All rights reserved.