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Manganese-catalysed C-H Functionalisation


School of Chemistry

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Dr S Thomas No more applications being accepted Competition Funded PhD Project (Students Worldwide)
Edinburgh United Kingdom Inorganic Chemistry Organic Chemistry Synthetic Chemistry

About the Project

Project Summary

This collaborative project between the Thomas group and AstraZeneca will develop manganese-catalysed C-H functionalisation reactions for the late-stage diversification of complex molecular architectures. A 3-month placement at AstraZeneca (Macclesfield, UK) form part of the studentship.

In the first instance, informal enquiries (accompanied by a CV) should be directed to:

Stephen Thomas, School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh EH9 3FJ, UK.  Email: [Email Address Removed]

The position will remain open until 22 Jan. 2021.

Equality and Diversity

The School of Chemistry holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. The University is a member of the Race Equality Charter and is a Stonewall Scotland Diversity Champion, actively promoting LGBT equality. The University has a range of initiatives to support a family friendly working environment. See our University Initiatives website for further information. University Initiatives website: https://www.ed.ac.uk/equality-diversity/help-advice/family-friendly


Funding Notes

A PhD studentship is available in the group of Stephen Thomas (School of Chemistry, The University of Edinburgh; http://www.thomas.chem.ed.ac.uk/. The studentship is in collaboration with AstraZeneca, Macclesfield UK, and is fully funded for 42 months. Funding covers tuition fees and an annual stipend (starting at £15,285 per annum) for a candidate satisfying EPSRC criteria:
https://www.epsrc.ac.uk/skills/students/help/eligibility/

References

Manganese-Catalysed Hydrofunctionlization of Alkenes. J. R. Carney, B. R. Dillon, L. Campbell, S. P. Thomas. Angew. Chem. Int. Ed. 2018, 57, 10620-10624.
Regiodivergent Hydrosilylation, Hydrogenation, [2+2]-Cycloaddition and C–H Borylation using Counterion Activated Earth-abundant Metal Catalysis. R. Agahi, A. J. Challinor, J. Dunne, J. H. Docherty, N. B. Carter, S. P. Thomas. Chem. Sci. 2019, 10, 5079-5084.
Iron-Catalysed C(sp2)-H Borylation Enabled by Carboxylate Activation. L. Britton, J. H. Docherty, A. P. Dominey, S. P. Thomas Molecules 2020, 25, 905.
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