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Masters by Research Project: Genomic Analysis of Antibacterial Drug Resistant Bacteria from Welsh Beef Farms

   School of Cellular and Molecular Medicine

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  Prof Matthew Avison, Dr K Reyher, Prof A Dowsey  No more applications being accepted  Funded PhD Project (UK Students Only)

About the Project

This Masters by Research project is funded by the Welsh Government as part of a large consortium grant looking at antibacterial drug usage and antibacterial drug resistance (ABR) on Welsh farms. The overall outcome will be to gain insights into the selection and transmission of ABR Escherichia coli on farms with a view to reducing it, and so the threat of resistant infections in humans and animals. This masters project fits within a workpackage aiming to characterise the mechanisms of ABR in E. coli on farms, and phylogenetic relationships between isolates. You will learn to perform primary sample processing and plating to recover ABR E. coli, susceptibility testing, molecular analysis of the resistant bacteria, whole genome sequencing and bioinformatic, including phylogenetic analysis. We will particularly focus on the presence of critically important mobile ABR mechanisms of relevance to human health on beef farms, and there will be an opportunity to test for evidence that these mechanisms are influencing human infections. This project benefits from being within a large, inter-disciplinary, One Health research consortium, providing the student with a wide range of training and networking opportunities.

Entry Requirements

2i honours degree in microbiology, molecular biology, biochemistry or a related subject. Experience working/studying in a bacteriology research lab would be an advantage.

You must be able to start the project in July 2022.

Funding Notes

Full UK fees are paid directly to the University. A stipend of £15,843.00 will be paid to the student, in instalments over 12 months.
The project must start in July 2022.
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