Ultrasound vibration potential (UVP) is an electroacoustic phenomenon due to an ultrasound applied to colloid particles or ionic electrolyte. Particles/ions in electrolyte media carry electrical charges. When excited, charged particles/ions vibrated and generate a secondary electric field that produces the so-called ultrasound vibration potential comprising two categories of Colloid vibration potential (CVP), or Ion vibration potential (IVP), reporting physicochemical features of particles or ions in the colloid or electrolyte along the path of the ultrasound, which has a high potential as a complementary imaging technology for process or medicine.
A number of testing devices have been designed (Leeds standard I - III) for ultrasound vibration potential imaging, which allows UVP can be non-intrusively detected. The proposed research focuses on develop novel methods of signal conditioning and processing for measuring the ultraweak UVP signal, which may involve the design of an excitation source to drive ultrasound phase array, high signal-to-noise ratio gate-amplifier, synchronised digital demodulation method and image reconstruction algorithm, to form part of the UVP research platform with existing facilities, which will be applied to one or more pilot studies in cancer research, membrane separation process and/or drug delivery. It is our expectation that the study will enable further research for developing an innovative technology for nanoparticle characterization in engineering and physicochemical imaging for medicine.