About the Project
This is a truly inter-disciplinary project led by a basic scientist and a clinical academic who will bring complementary areas of expertise. The project will equip the student with a range of versatile skills including bioinformatic analysis of human genome/exome sequences, cell culture, modelling human disease in model organisms and cloning/transgenesis techniques such as CRISPR. The skills and knowledge provided by project will provide a solid foundation for a future career in disease-gene discovery, precision medicine, translational medicine or neuroscience.
This project will provide training in a diverse array of techniques including bioinformatic analysis of human genomic and exomic sequences, cell culture methods including transfection and immunocytochemistry, molecular biology methods including PCR, site directed mutatagenesis and CRISPR, Drosophila genetic approaches and a variety of imaging techniques including confocal microscopy.
Candidates are expected to hold (or be about to obtain) a minimum upper second class honours degree (or equivalent) in a biological or medical science. The project would suit a candidate interested in using model organism and cell culture approaches to understand human disease.
For international students we also offer a unique 4 year PhD programme that gives you the opportunity to undertake an accredited Teaching Certificate whilst carrying out an independent research project across a range of biological, medical and health sciences. For more information please visit http://www.internationalphd.manchester.ac.uk
As an equal opportunities institution we welcome applicants from all sections of the community regardless of gender, ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.
Disorders with Diverse Phenotypes. Am. J. Hum. Genet. (2017) 101 466-477.
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