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Mechanistic dissection of interplay between membrane traffic and apoptosisby mutations in the endosomal sorting regulatory protein Vps45.


Project Description

Eukaryotic cells have to coordinate a large number of cellular processes in
order to function properly. Understanding how this is achieved is critical for
many areas of the biosciences. The protein Vps45 regulates membrane
traffic through the endosomal system and also plays a role in preventing cells
from entering programmed cell death (apoptosis). This project will use a
combination of yeast genetics, cell biology and biochemistry to understand
how these two critical cellular pathways are interrelated.

Funding Notes

This studentship is fully funded for four years and covers: (i) a tax-free annual stipend at the standard Research Council rate (£15,009 estimated for 2020 entry), (ii) research costs, and (iii) tuition fees at the UK/EU rate.

References

Entry requirements: Students with, or expecting to gain, at least an upper second class honours degree, or equivalent, are invited to apply. The interdisciplinary nature of this research project means that we welcome applications from students with backgrounds in any biological, chemical, and/or physical science, or students with mathematical backgrounds who are interested in using their skills in addressing biological questions.

Related Subjects

How good is research at University of York in Biological Sciences?

FTE Category A staff submitted: 44.37

Research output data provided by the Research Excellence Framework (REF)

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