Biomedical sensing is an area of wide-ranging importance with significant fundamental and applied research that continues to push the limits, in terms of analytical targets, sensitivity, robustness and versatility. Resistive-pulse sensors, such as solid-state nanopores and nanopipettes, are particularly interesting here, because they are a class of single-molecule sensors with unique capabilities and they can be augmented using engineered and functional DNA nanostructures ("carrier-enhanced" resistive-pulse sensing).
In this project, we will expand this concept, using DNA nanotechnology and self-assembly, to create novel "mesocopic" devices, where sensor readout is performed multiple, potentially thousands of times, to achieve unprecedented levels of accuracy and reproducibility.
This is a highly interdisciplinary project, involving nanofabrication, DNA self-assembly, electronics, automation and advanced data analysis. The ideal candidate would therefore have a background in chemistry or physics, or in a related area, be collaborative and importantly should have willingness and enthusiasm to be challenged and learn new things. Previous coding experience in Matlab or Python is advantageous, but not a must.
If you have any questions or would like to request further information, please get in touch via email ([Email Address Removed]) or check out our group website at https://albrechtlab.com/.
For information on how to apply, please visit our home page at the link below: https://www.birmingham.ac.uk/postgraduate/courses/apply-pg/index.aspx