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Messenger RNA therapeutics to promote epithelial repair


   National Heart and Lung Institute

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  Dr Asha Patel, Prof Robert Snelgrove  No more applications being accepted  Funded PhD Project (Students Worldwide)

About the Project

3-year NHLI-funded PhD.

Application deadline: Wednesday 31st August 2022

Start date: 1st November 2022

Applications are invited from candidates with a Master’s degree and undergraduate training in life sciences or pharmaceutical sciences, for a PhD studentship exploring nucleic acid therapeutics for epithelial repair. 

The studentship will be funded for 3 years with a tax-free bursary of £18,000 per annum. Tuition fees at the Home and Ireland rate will also be paid.

The project will investigate how proteins such as growth factors or cytokines can direct lung repair. Pulmonary fibrosis (PF) is one such condition where aberrant repair plays a role in disease. Synthetic messenger RNA will encode reparative factors to explore whether nucleic acids can promote wound healing. The studentship will be based in the Inflammation, Repair & Development Section which is within the Respiratory Division of the National Heart & Lung Institute and provides a stimulating environment of basic scientists and clinicians working across themes of airway regeneration, immunology, and translational lung research. The PhD candidate will have the opportunity to bring together multiple disciplines of epithelial cell biology, non-viral vector formulation and lung physiology.

The studentship has been made possible by the National Heart and Lung Institute (NHLI), and will be supervised by Dr Asha Patel and Professor Robert Snelgrove. We expect the PhD to begin 1st November 2022.

The NHLI provides an exciting environment, with state of the art facilities and excellent opportunities for PhD student training. All students will belong to Imperial’s award-winning Graduate School which provides a comprehensive Professional Skills Programme.

Funding notes

Studentships include funding for Home tuition fees plus stipend (£18,000 per annum).

  • UK/EU/International candidates may apply.
  • Successful non-UK candidates must pay the difference between Home and International tuition fees (this difference was £34,300 per year for the 3 years of study 2021/2). 

How to Apply

Applicants must hold, or expect to obtain, a first or upper second-class undergraduate degree or UK equivalent, along with a Masters, both in an appropriate subject from a recognised academic institution. 

To apply please email the following information to Dr. Asha Patel at [Email Address Removed]

  • Curriculum Vitae (max 2 pages)
  • Personal statement (1 page)
  • Name, address, telephone number or email of two referees. At least one of which must be academic.

Applicants unable to attend interview in person will undergo an online interview and be invited for a second face-to-face meeting before confirmation of offer.

Please note that candidates must fulfil College admissions criteria.

Committed to equality and valuing diversity. We are also an Athena SWAN Silver Award winner, a Stonewall Diversity Champion, a Disability Confident Employer and are working in partnership with GIRES to promote respect for trans people.

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