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Metabolic response after experimental stroke


Project Description

Project Description

The Translational Stroke and Dementia Research Group (Prof. M. Dichgans) at the Institute for Stroke and Dementia Research at LMU, Munich, Germany invites applications for an Early Stage Researcher/Ph.D. position.
The successful candidate will work on the systemic metabolic response following stroke, with a focus on catabolic processes and their effectors. The project is funded by funds of the medical faculty of the LMU Munich. The successful applicant will be part of an international team of investigators and will participate in the design of experiments, will apply experimental stroke models, biochemical methods, and imaging modalities, and will perform data collection and analysis.


Job description

You will work on a research project with the following objectives:

• Provide a detailed account of the kinetics of the metabolic response after experimental stroke using metabolite measurements, biochemical methods, and imaging modalities
• Study the underlying biochemical processes such as glucose homeostasis and proteolysis utilizing biochemical methods, isotopic labeling, and imaging
• Explore strategies to modify the catabolic state as a potential basis for future therapies
• In collaboration with other members of the group, utilize available metabolomics data from human ischemic stroke patients to determine the overlap between human and experimental stroke

You will be working in a multidisciplinary team with extensive expertise in experimental stroke, imaging, genetics, and biomarker discovery, have full access to the extensive facilities available at the Institute for Stroke and Dementia Research, engage in national and international collaborations and take part in the international training programme of the Center for Stroke and Dementia Research. In addition, there is the possibility to apply for enrollment in the Graduate School for Systemic Neuroscience (GSN), to which our Institute is affiliated.


Requirements

We are looking for a highly motivated self-driven student with a strong commitment to experimental stroke research, who:
• Has a MSc degree in biology, biomedical sciences, or related disciplines
• Enjoys working with experimental stroke models
• Is a team player with good communication skills

Funding Notes

Appointment terms

The successful candidate will receive a salary in accordance to the TV-L. The period of employment is three years.
Starting date: January – April 2020. Disabled persons will be preferentially considered in case of equal qualification.
Presentation costs cannot be refunded.

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