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Metabolism of vascular anomalies

  • Full or part time
  • Application Deadline
    Wednesday, May 01, 2019
  • Funded PhD Project (Students Worldwide)
    Funded PhD Project (Students Worldwide)

Project Description

The Angiogenesis & Metabolism Laboratory at the Max Planck Institute for Heart and Lung Research invites applications for an Early Stage Researcher/Ph.D. position. The successful candidate will focus on the metabolism of vascular anomalies with the aim to understand the role and therapeutic potential of endothelial metabolic adaptions in these vascular diseases. The project is part of the EU-MSCA-ETN project V.A. Cure, which aims to uncover mechanisms that drive the formation and maintenance of vascular anomalies with the final goal to establish novel therapeutic approaches. The project is funded in the frame of the EU MSCA-ITN programme, and successful applicants will be part of an international team of 14 Ph.D. students jointly working on the V.A. Cure project.

Job description
You will work on a research project with the following objectives:
• Characterize metabolic adaptations in endothelial cells of in blood and lymphatic vascular malformations
• Identify (transcriptional) mechanisms that govern endothelial metabolic adaptations in vascular anomalies
• Generate mouse of models of perturbed (metabolic) pathways to test the therapeutic potential
• Screen for mutations in metabolic regulators in patients with blood and lymphatic anomalies
You will have full access to all the facilities available at the Max Planck Institute, and you will also take part in the international training programme of the network.

Requirements
We are looking for a motivated student with a strong commitment to basic research, who:
• is eligible for MSCA-ETN funding, see Funding Notes
• has an MSc degree in biology, biomedical sciences, or related disciplines
• is a team player with good communication skills

Appointment terms
The successful candidate will receive an attractive salary in accordance with MSCA regulations for Early Stage Researchers. The period of employment is three years. Starting date: June – October 2019.

How to apply
– Make sure you meet the qualifying requirements.
– Submit your application to by e-mail, mentioning ‘application for ESR11’ in the subject line. Please send one pdf file containing:
• A motivation letter describing your research career goals, skills and experience (cover letter)
• Curriculum vitae
• Grade transcripts and BSc/MSc diploma (in English or with a translation into English)
• Two letters of recommendation or the contact information for at least 2 referees.

Deadline for submitting applications: 1 May 2019

More information
Please visit http://www.vacure.eu for more information on the project, the recruitment and selection criteria. Contact for questions: .

The Max Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. Furthermore, The Max Planck Society strives for gender and diversity equality. We welcome applications from all backgrounds.

Funding Notes

To be eligible for this H2020-MSCA-ITN funded PhD student position, you must:
– not have resided or carried out your main activity (work, studies, etc.) in the country of the recruiting beneficiary for more than 12 months in the 3 years immediately before the recruitment date. Compulsory national service, short stays such as holidays, and time spent as part of a procedure for obtaining refugee status under the Geneva Convention are not taken into account, and
– At the date of recruitment (=first day of employment), be in the first four years (full-time equivalent research experience) of your research career and not have been awarded a doctoral degree.

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