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Microenvironmental mechanics in epithelial morphogenesis and tumorigenesis

   Faculty of Medicine

  Dr Zuzana Sumbalová Koledová  Applications accepted all year round  Funded PhD Project (Students Worldwide)

About the Project

Affiliation: Masaryk University, Faculty of Medicine

Study program: PhD program Biomedical Sciences

Specialization: Cell and Tissue Morphology

Workplace: Department of Histology and Embryology, Faculty of Medicine

Mode: Full-time

Supervisor: Mgr. Zuzana Sumbalova Koledova, Ph.D.

Lab website:

Brief annotation:

The Sumbalova Koledova research group: Mechanisms of epithelial morphogenesis aims to unravel critical mechanisms of organ formation and tumorigenesis. To this end, we use an interdisciplinary approach employing organoids, genetic mouse models, single-cell and spatial genomics, biosensors, state-of-the-art imaging techniques, mathematical modelling, and AI-driven image analysis. The PhD project will tackle the role microenvironmental mechanics in epithelial morphogenesis and tumorigenesis using iterative biological experimentation in mammary epithelial organoids by the PhD candidate and computational modelling by mathematically oriented engineers in our team.

Funding: Czech Science Foundation (GAČR)


  • Highly motivated, passionate, self-driven and creative candidates with MSc (or equivalent) in cell, developmental or molecular biology or related areas
  • Interest in developmental biology and fundamental processes of life
  • Excellent communication skills, ability to work in an interdisciplinary team
  • Previous experience with cell and organoid culture is advantageous but not essential
  • Willingness to travel abroad for meetings and research internships

Active knowledge of English Publications from the Sumbalova Koledova group:

For the latest information about our research activity, follow Twitter account @KoledovaZuzana

Informal inquiries about the PhD topic are welcome at

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