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Modelling muscle disease in zebrafish – Investigating the Role of the Immune System in Duchenne Muscular Dystrophy


Project Description

The Myopathy Research Team in at Monash University, Melbourne, Australia http://www.myopathyresearch.org is looking for a PhD student to work on an exciting new project, funded by Muscular Dystrophy Australia http://www.mda.org.au and supervised by Dr Tamar Sztal. The aim of the project is to study inflammation in Duchenne Muscular Dystrophy (DMD) and the effect on necrosis and regeneration. We are seeking highly motivated and enthusiastic applicants with experience in molecular biology, developmental biology/genetics, and, ideally, someone who has previously worked with zebrafish.

Project Details
Zebrafish are a very useful model to study muscle disease. Using the advantages of the zebrafish system to visually track and monitor muscle damage in the living fish, this project investigates the contribution of the immune response and associated oxidative stress to increase muscle wasting in a zebrafish model of DMD. Results of this research has important implications for the fundamental understanding of the pathogenesis of DMD and potential therapeutic avenues to reduce muscle damage and strengthen growing fibres.

Scholarship Details
Scholarships covering tuition fees and providing a living allowance of AUD$27,872 per year are available to both Australian and international students as well as an allowance for conference travel.

MONASH UNIVERSITY, School of Biological Sciences
Monash University is the largest university in Australia and is consistently ranked in the top 100 universities in the world and is ranked in the top 50 for Biological Sciences. The School of Biological Sciences provides an outstanding scientific environment in which to undertake a PhD. It is home to world-renowned researchers in a range of biological disciplines providing a highly collaborative and supportive environment. We have a large and dynamic postgraduate community with students drawn from a wide range of nationalities, cultures, and backgrounds. This creates a productive scientific environment as well as an active social atmosphere.

APPLICATION PROCESS
Interested applicants must compete the online questionnaire:
https://docs.google.com/forms/d/16LvlXtTA5mkV8WfrvAfB8Mg9Q3dJBXKbJsfRDjYobR0/viewform

The applicant must have a MSc (research) or BSc or equivalent degree in genetics, developmental biology, or related discipline including a research project of at least 6 months full time (or equivalent) duration.

Minimum English language requirements; IELTS 6.5 overall (no less than 6 in any category), TOEFL ibt 79 (at least 21 writing, 18 for speaking, 13 reading, 12 listening); or to be from, or have a tertiary qualification with at least 2 years study from, a country with English as the primary language.

Funding Notes

Scholarships covering tuition fees and providing a living allowance of AUD$27,872 per year are available to both Australian and international students as well as an allowance for conference travel.

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