Molecular analysis of TERT gene promoter mutations in tongue cancer at Queen Mary University of London on FindAPhD.com

Dr Angray Kang , Prof E K Parkinson Applications accepted all year round Self-Funded PhD Students Only

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London United Kingdom Cancer / Oncology Dentistry Medical / Clinical Science

Institute of Dentistry, Queen Mary University of London

About the Project

Background:

Activation of telomerase is a hallmark of cancer and is aided in some tumours by activating mutations in the promoter of the telomerase reverse transcriptase gene, TERT.
Squamous cell carcinoma of the tongue is a serious disease even its early stages and we have detected TERT gene promoter mutations in 83% of dysplasia making them potential non-invasive detectors of early stage disease in saliva or blood.

Aims:

- Test for TERT promoter mutations in pre-malignant oral samples with different progression outcomes.
- Develop sensitive tests to identify TERT promoter mutations in liquid biopsies.

How to apply:

For more information regarding the project, please contact Dr A. Kang (a.s.kang@qmul.ac.uk).

Applications should be submitted through the Queen Mary application system: https://www.qmul.ac.uk/postgraduate/research/subjects/dentistry.html

Please indicate the project title and supervisor in the ‘Research Degree Programmes - Additional Questions’ section of the application.

Alongside the application form, please send the following supporting documents:
• Curriculum Vitae (CV)
• Copies of your degree certificates with transcripts
• Proof of English language ability for overseas applicants from non-English speaking countries
• A one-side A4 statement of purpose. This should set out your previous academic or other experience relevant to the proposed research; why you wish to undertake this research at QMUL; your previous research or professional training and what further training you think you will need to complete a PhD; and what ethical issues you will need to consider in undertaking this research.
• Two references. At least one reference must be from an academic referee who is in a position to comment on the standard of your academic work and suitability for postgraduate level study. Where appropriate, a second referee can provide comment on your professional experience.

Please contact dentistrypgr@qmul.ac.uk with any queries about the application process.

Funding Notes

We will consider applications from prospective students with a source of funding to cover tuition fees and bench fees for three years full-time or 6 years part-time. Both self-funded and sponsored students will be considered.

UK and EU nationality self-funded students might be eligible for both the cost of tuition fees and a yearly stipend over the course of the PhD programme from the Student Finance England: View Website

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Molecular analysis of TERT gene promoter mutations in tongue cancer

Queen Mary University of London Institute of Dentistry

About the Project

Background:

Aims:

How to apply:

Funding Notes