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Molecular mechanism of transcriptional regulation by nuclear hormone receptors

  • Full or part time
  • Application Deadline
    Thursday, February 28, 2019
  • Funded PhD Project (Students Worldwide)
    Funded PhD Project (Students Worldwide)

About This PhD Project

Project Description

PhD studentship in Biomedical Sciences (to be admitted in mid-August 2019)

The laboratory of Professor Edwin Cheung is seeking highly motivated PhD candidates to perform research on gene regulation in breast and prostate cancer.

Our group’s main interest is to understand the molecular details of nuclear hormone signaling and how these pathways relate to diseases such as cancer. Specifically, we are investigating how steroid hormones such as estrogens and androgens regulate the transcriptional activities of nuclear hormone receptors. We achieve this by employing a multi-disciplinary approach combining powerful biological tools, including modern genetic and cell-based techniques (RNAi, smFISH, and CRISPR/Cas) and next-generation sequencing approaches (ChIP-Seq, RNA-Seq, and single cell analysis), to define the molecular mechanisms of transcriptional regulation by estrogen and androgen receptors.

The appointed student will participate in research on understanding how genes are precisely regulated at the transcriptional level in cancer. He/she will be given the opportunity to master and develop state-of-the-art molecular, cell, and genomic technologies as well as learning new techniques from collaborators’ laboratories.

Applicants must hold a bachelor or master degree in relevant areas of biomedical sciences. Previous experience in molecular and cell biology or bioinformatics is preferred. Candidates recruited from high-ranking universities can also apply for the “UM Macao PhD Scholarship” (MPDS) which offers annual stipend up to MOP240,000 (about USD30,000) for a period up to 4 years. Please visit the Graduate School’s website (https://www.umac.mo/grs/en/index.php) for details of the MPDS.

To apply, please contact Professor Edwin CHEUNG at .

Application Deadline
28 February 2019

Normative Study Period
4 years

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