This project is no longer listed in the FindAPhD
database and may not be available.
This project is competition funded for students worldwide.
If successful the student would receive full tuition fee payment for 3.5 years as well as a tax free stipend amounting to £21,000pa paid in monthly instalments for the duration of their studentship.
Whilst Overseas Students are eligible, funding is more limited so only exceptional OS students will be considered.
Hill PWS, Leitch HG, Requena C, Sun Z, Amouroux R, Trufero M, Borkowska G, Terragni J, Vaisvila R, Linnett S, Dharmalingham G, Haberle V, Lenhard B, Zheng Y, Pradhan S, Hajkova P: Germline epigenetic reprogramming enables primordial germ cell-to-gonocyte transition in mouse. Nature, 2018 Mar 15;555(7696):392-396. doi: 10.1038/nature25964. Epub 2018 Mar 7
Leitch HG, Hajkova P. :Eggs sense high fat diet. Nat Genet. 2018 Mar;50(3):318-319. doi: 10.1038/s41588-018-0068-1
Rošić S*, Amouroux R*, Requena C*, Linnett S, Selkirk ME, Emperle M, Jeltsch A, Schiffer PH, Bancroft A, Grencis R, Hajkova P+ and Sarkies P+: Evolutionary analysis reveals DNA alkylation damage is a byproduct of cytosine DNA methyltransferase activity. Nat Genet. 2018 Mar;50(3):452-459. doi: 10.1038/s41588-018-0061-8. Epub 2018 Feb 19 (+ senior co-authors).
Amouroux, R., Nashun, B., Shirane, K., Nakagawa, S., Hill, P. W. S., D'Souza, Z., Nakayama M, Matsuda M, Turp A, Ndjetehe E, Encheva V, Kudo N, Koseki H, Sasaki H and. Hajkova, P. : De novo DNA methylation drives 5hmC accumulation in mouse zygotes. Nat Cell Biol, 2016 18(2), 225
Nashun B., Hill P.W.S., Smallwood S.A., Dharmalingam G., Amouroux R., Clark S.J., Sharma V., Ndjetehe E, Pelczar P, Festenstein R, Kelsey G and Hajkova P.: Continuous Histone Replacement by Hira Is Essential for Normal Transcriptional Regulation and De Novo DNA Methylation during Mouse Oogenesis. Mol Cell 2015, 60(4), 611-625.
Nashun B, Hill PW, Hajkova P.: Reprogramming of cell fate: epigenetic memory and the erasure of memories past. EMBO J. 2015 May 12;34(10):1296-308.
Leitch HG, McEwen KR, Turp A, Encheva V, Carroll T, Grabole N, Mansfield W, Nashun B, Knezovich JG, Smith A, Surani MA, Hajkova P.: Naive pluripotency is associated with global DNA hypomehtylation. Nat Struct Mol Biol. 2013 Feb 17;20(3):311-6.
Hajkova P, Jeffries SJ, Lee C, Miller N, Jackson SP, Surani MA: Genome wide reprogramming in mouse germ line entails the Base Excision Repair pathway. Science. 2010 Jul 2;329(5987):78-82.
Hajkova P. Ancelin K, Waldmann T, Lacoste N, Lange UC, Cesari F, Lee C, Almouzni G, Schneider R and MA Surani: Chromatin dynamics in the process of epigenetic reprogramming in the mouse germ line. Nature. 2008 Apr 17;452(7189):877-81.