Applications are invited from self-funded students. For UK/EU tuition fees are £15,500 and International are £30,500 for 2019/20 academic year.
Candidates are expected to hold (or be about to obtain) a minimum upper second class honours degree (or the overseas equivalent) in a related area / subject. Candidates with experience in molecular biology or with an interest in structural biology and NMR spectroscopy are encouraged to apply.
Please select PhD Biological Chemistry on the online application form.
Tunnicliffe RB, Collins RF, Ruiz Nivia HD, Sandri-Goldin RM, Golovanov AP. The ICP27 Homology Domain of the Human Cytomegalovirus Protein UL69 Adopts a Dimer-of-Dimers Structure. MBio. 2018 Jun 19;9(3). pii: e01112-18. doi: 10.1128/mBio.01112-18.
Tunnicliffe RB, Lockhart-Cairns MP, Levy C, Mould AP, Jowitt TA, Sito H, Baldock C, Sandri-Goldin RM, Golovanov AP. The herpes viral transcription factor ICP4 forms a novel DNA recognition complex. Nucleic Acids Res. 2017 Jul 27;45(13):8064-8078. doi: 10.1093/nar/gkx419.
Tunnicliffe RB, Schacht M, Levy C, Jowitt TA, Sandri-Goldin RM, Golovanov AP. The structure of the folded domain from the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer. Sci Rep. 2015 Jun 11;5:11234. doi: 10.1038/srep11234.
Tunnicliffe RB, Hautbergue GM, Wilson SA, Kalra P, Golovanov AP. Competitive and cooperative interactions mediate RNA transfer from herpesvirus saimiri ORF57 to the mammalian export adaptor ALYREF. PLoS Pathog. 2014 Feb 13;10(2):e1003907. doi: 10.1371/journal.ppat.1003907.
Tian X, Devi-Rao G, Golovanov AP, Sandri-Goldin RM. The interaction of the cellular export adaptor protein Aly/REF with ICP27 contributes to the efficiency of herpes simplex virus 1 mRNA export. J Virol. 2013 Jul;87(13):7210-7. doi: 10.1128/JVI.00738-13.