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Molecular technologies for synthetic and systems biology

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  • Full or part time
    Dr K Sarkisyan
  • Application Deadline
    No more applications being accepted
  • Competition Funded PhD Project (Students Worldwide)
    Competition Funded PhD Project (Students Worldwide)

Project Description

We are a small new lab in the Integrative Biology section of the LMS consisting of two humans and two robots. We are looking for someone with a genuine interest in understanding and engineering biology, with extensive wet lab experience and, preferably, good coding skills.

We love high-throughput assays, automation and light-based biotechnologies and work in several research directions, both basic and applied.This research project ranges from designing and performing high-throughput assays for analysis of structure-function relationship in proteins to engineering cells that are able to perform directed evolution without human involvement. We also plan to work on development of optical life-life and life-computer communication interfaces based on a combination of emerging optogenetic and bioluminescent technologies.

Previous experience with various DNA assembly techniques is desirable, as well as coding skills in Python. Experience in synthetic biology is a plus.

For more information, please visit our website: https://www.designing.bio

Funding Notes

This project is competition funded for students worldwide.

If successful the student would receive full tuition fee payment for 3.5 years as well as a tax free stipend amounting to £21,000pa paid in monthly instalments for the duration of their studentship.

Whilst Overseas Students are eligible, funding is more limited so only exceptional OS students will be considered.

References

Alexey Kotlobay*, Karen S. Sarkisyan*#, Yuliana Mokrushina*, Marina Marcet-Houben*, Ekaterina O. Serebrovskaya*, Nadezhda M. Markina, Andrei Y. Gorokhovatsky, Konstantin V. Purtov, Valentin N. Petushkov, Natalja S. Rodionova, Tatiana V. Chepurnykh, Liliia I. Fakhranurova, Louisa Gonzalez Somermeyer, Elena B. Guglya, Rustam Ziganshin, Aleksandra S. Tsarkova, Zinaida M. Kaskova, Victoria Shender, Maksim Abakumov, Tatiana Abakumova, Inna S. Povolotskaya, Fyodor Eroshkin, Andrey Zaraisky, Alexander S. Mishin, Sergey V. Dolgov, Maria D. Logacheva, Nikolay Zolotarev, Eugene P. Kopantzev, Hans Waldenmaier, Anderson G. Oliveira, Yuichi Oba, Ekaterina Barsova, Ekaterina A. Bogdanova, Toni Gabaldón, Cassius V. Stevani, Ivan V. Smirnov, Josef I. Gitelson, Sergey Lukyanov, Fyodor A. Kondrashov, and Ilia V. Yampolsky#, “A genetically encodable bioluminescent system from fungi”, PNAS, 2018, in press.
* equal contribution. # corresponding authors.

Karen S. Sarkisyan*, Dmitry A. Bolotin*, Margarita V. Meer, Dinara R. Usmanova, Alexander S. Mishin, George V. Sharonov, Dmitry N. Ivankov, Nina G. Bozhanova, Mikhail S. Baranov, Onuralp Soylemez, Natalya S. Bogatyreva, Peter K. Vlasov, Evgeny S. Egorov, Maria D. Logacheva, Alexey S. Kondrashov, Dmitry M. Chudakov, Ekaterina V. Putintseva, Ilgar Z. Mamedov, Dan S. Tawfik, Konstantin A. Lukyanov, Fyodor A. Kondrashov. “Local fitness landscape of the green fluorescent protein”. Nature, 2016, 533, 397–401 doi:10.1038/nature17995.
* equal contribution.



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