This is a CASE studentship in partnership with UCB and will be funded under the MRC Doctoral Training Programme. If you are interested in this project, please make direct contact with the Supervisor to discuss the project further as soon as possible. You MUST also submit an online application form - full details on how to apply can be found here View Website.
As an equal opportunities institution we welcome applicants from all sections of the community regardless of gender, ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.
Eyes TJ, Austerberry JI, Dearman RJ, Johannissen LO, Kimber I, Smith N, Thistlethwaite A, Derrick JP (2019) Identification of B cell epitopes enhanced by protein unfolding and aggregation. Mol Immunol 105: 181-189
Gurjar SA, Derrick JP, Dearman RJ, Thorpe R, Hufton S, Kimber I, Wadhwa M (2017) Surrogate CD16-expressing effector cell lines for determining the bioactivity of therapeutic monoclonal antibodies. J Pharm Biomed Anal 143: 188-198
Rane SS, Dearman RJ, Kimber I, Uddin S, Bishop S, Shah M, Podmore A, Pluen A, Derrick JP (2019) Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies. Pharmaceutical Research 36: 51
Ratanji K, Dearman R, Kimber I, Thorpe R, Wadhwa M, Derrick J (2016) Subvisible aggregates of immunogenic proteins promote a Th1-type response. Toxicol Sci 153: 258-270
Ratanji KD, Derrick JP, Kimber I, Thorpe R, Wadhwa M, Dearman RJ (2017) Influence of Escherichia coli chaperone DnaK on protein immunogenicity. Immunology 150: 343-355