Recent work from the lab can be found in the following references:
1) Cuadrado A, Rojo AI, .., Dinkova-Kostova AT. Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases. Nature Reviews Drug Discovery. 18,295–317 (2019).
2) Bueren-Calabuig JA, Bage MG, Cowling VH, Pisliakov AV. Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: insights from accelerated molecular dynamics simulations. Nucleic Acids Research. 47 8675–8692 (2019). Varshney D, Petit AP, Bueren-Calabuig JA, Jansen C, Fletcher DA, Peggie M, Weidlich S, Scullion P, Pisliakov AV, Cowling VH. Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM. Nucleic Acids Research.44, 10423-36 (2016).
3) Carvalheda CA, Pisliakov AV. Insights into proton translocation in the cbb3 oxidase from large scale MD simulations. Biochem. Biophys. Acta -Bioenerg. 1858, 396-406 (2017).