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(MRC DTP) Individual exposure to airborne exposures assessed by using personal monitoring devices


   Faculty of Biology, Medicine and Health

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  Prof Martie van Tongeren, Dr Tom Bannan, Dr E Johnstone, Dr A Povey  No more applications being accepted  Competition Funded PhD Project (Students Worldwide)

About the Project

Exposure to air pollutants have been shown to adversely affect birth outcomes and determimental to children’s health, However, further work is required to better characterise individual exposures and critical time windows of exposure so as to improve our knowledge on the associatons between these exposures and ill-health. The overall aim of this project is to characterise individual parental pre, ante and post-natal exposures. This project will then specifically investigate (i) the feasibility of using different individual monitoring devices and methodologies that have been reported to assess airborne exposures in a population of women attending an infertility clinic for treatment and then (ii) use appropriate devices and methods to assess this exposure and the determinants of such exposure in an existing longitudinal study of pregnant women. Training not only in quantitative skills (e.g. exposure modelling), but also in epidemiological studies and laboratory/exposome studies will be provided as an intrinsic part of the project.  In the feasibility study, recruited women will be asked to wear portable (active and passive) monitoring devices and keep a daily diary of activities that can affect airborne exposures. Whether such devices are acceptable in this population will be assessed and suitable devices will then be used in a large cohort study. In this study, airborne exposures will be modelled and also assessed by indoor air quality sensors and results from these approaches will be validated by the use of personal monitoring devices. Results of the air pollution measurements and modelling will be linked to outcome data, such as birth weight. In addition, these results will also have a significant impact of determining the applicability of such devices to wider population studies of air pollution induced ill-health.

Prof Professor Martie Van Tongeren | The University of Manchester 

Entry Requirements

Applicants must have obtained or be about to obtain a First or Upper Second class UK honours degree, or the equivalent qualifications gained outside the UK, in an appropriate area of science, engineering or technology.

How to Apply

To be considered for this project you MUST submit a formal online application form - full details on how to apply can be found on the MRC Doctoral Training Partnership (DTP) website www.manchester.ac.uk/mrcdtpstudentships 

Applicants interested in this project should make direct contact with the Primary Supervisor to arrange to discuss the project further as soon as possible.

Equality, Diversity and Inclusion

Equality, diversity and inclusion is fundamental to the success of The University of Manchester, and is at the heart of all of our activities. The full Equality, diversity and inclusion statement can be found on the website https://www.bmh.manchester.ac.uk/study/research/apply/equality-diversity-inclusion/


Funding Notes

Funding will cover UK tuition fee and stipend only. The University of Manchester aims to support the most outstanding applicants from outside the UK. We are able to offer a limited number of scholarships that will enable full studentships to be awarded to international applicants. These full studentships will only be awarded to exceptional quality candidates, due to the competitive nature of this scheme.

References

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2. Newland MJ, Bryant DJ, Dunmore RE, Bannan TJ, Acton WJF, Langford B, Hopkins JR, Squires FA, Dixon W, Drysdale WS, Ivatt PD, Evans MJ, Edwards PM, Whalley LK, Heard DE, Slater EJ, Woodward-Massey R, Ye C, Mehra A, Worrall SD, Bacak A, Coe H, Percival CJ, Hewitt CN, Lee JD, Cui T, Surratt JD, Wang X, Lewis AC, Rickard AR, Hamilton JF. Low-NO atmospheric oxidation pathways in a polluted megacity, Atmos Chem Phys 2021; 21: 1613–1625.
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4. Belut E, Sánchez Jiménez A, Meyer-Plath A, Koivisto AJ, Koponen IK, Jensen ACØ, MacCalman L, Tuinman I, Fransman W, Domat M, Bivolarova M, van Tongeren M. Indoor dispersion of airborne nano and fine particles: Main factors affecting spatial and temporal distribution in the frame of exposure modelling. Indoor Air 2019;29:803-16.
5. McFiggans, G., Mentel, T.F., Wildt, J. Pullinen I, Kang S, Kleist E, Schmitt S, Springer M, Tillman R, Wu C, Zhao D, Hallquiat M, Faxon C, Le Breton M, Hallquist AM, Simpson D, Bergstrom R, Jenkin ME, Ehn M, Thornton JA, Alfarra MR, Bannan TJ, Percival CJ, Priestly M, Topping D, Kiendler-Scharr A. Secondary organic aerosol reduced by mixture of atmospheric vapours. Nature 2019;565: 587–593.