People suffering from severe mental illnesses (such as depression, schizophrenia and bipolar disorder) have a substantially risk of obesity, diabetes and cardiovascular disease. Reasons for this are unclear, but could be due medication, socioeconomic or lifestyle factors or shared pathological mechanisms. This project use genetic predisposition to serious mental illness to explore whether severe mental illness promotes storage of fat tissue in a way that leads to diabetes and heart disease.
The project will use edpidemiology and statistical genetic approaches, using publicly available data and the UK Biobank study which has extensive genetic and clinical information. This project provides the opportunity to conduct research of global relevance with state of the art resources and in collaboration with leading experts in psychiatric, metabolic and cardiovascular genetics as well as experts in clinical trials of weight-loss intervention.
The student will be trained in the required methods within a data science framework. They are expected to have a BSc or MSc in a relevant field, with an understanding of genetics and statistics. Experience in data science and/or statistical genetics is an advantage.
Project Q&A Session
Wednesday 30th November, 1000 hrs.
Email: [Email Address Removed] for password information.
About the Programme
This MRC programme is joint between the Universities of Edinburgh and Glasgow. You will be registered at the host institution of the primary supervisor detailed in your project selection.
All applications should be made via the University of Edinburgh, irrespective of project location. For those applying to a University of Glasgow project, your application along with any supporting documents will be shared with University of Glasgow.
How to Apply: https://www.gla.ac.uk/colleges/mvls/graduateschool/mrcdtpprecisionmedicine/howtoapply/
Please note, you must apply to one of the projects and you must contact the primary supervisor prior to making your application. Additional information on the application process is available here: http://www.ed.ac.uk/studying/postgraduate/degrees/index.php?r=site/view&id=919
For more information about Precision Medicine visit:
[Email Address Removed]