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MRC Precision Medicine DTP: Development of a SMART biosensor of remote diagnosis and therapy in vascular access for cardiovascular disease

  • Full or part time
  • Application Deadline
    Wednesday, January 08, 2020
  • Competition Funded PhD Project (European/UK Students Only)
    Competition Funded PhD Project (European/UK Students Only)

Project Description

Dr John Mercer
Dr Srinjoy Mitra

Project summary:
Despite significant improvements in healthcare provision, cardiovascular disease remains the number one cause of death in the Western World. Atherosclerosis is the pathological condition that underlies two thirds of Heart attacks and Strokes that contribute to more than 4.3 million premature deaths in Europe per annum. The economic burden to the European Union for cardiovascular disease is estimated at over €196 Billion. The current clinical approaches of stenting coronary artery atherosclerotic plaques and surgical resection have significant risk and associated costs. This proposal builds on an established multidisciplinary project to develop a SMART self reporting stent that can be deployed using existing methods, yet provides advanced technological properties that are predicted to reduce patient morbidity and mortality. An implantable stent device which can interact and report on its own vessel status would have profound benefit to physicians. One that can then respond by altering the local environmental conditions would be transformative. This project will be based at the British Heart Foundation Cardiovascular Research Centre, University of Glasgow and the Scottish Microelectronics Centre, Edinburgh. This project is suitable for diligent bio/engineer/physics student who is keen to apply their theoretical knowledge to real world problems. You will be part of a supportive team of basic scientists, engineers and NHS clinicians working towards developing the next generation of implantable devices. Opportunities exist for international travel to collaborators and partners facilities.

This MRC programme is joint between the Universities of Edinburgh and Glasgow. You will be registered at the host institution of the primary supervisor detailed in your project selection.

All applications should be made via the University of Edinburgh, irrespective of project location. Please note that your application along with any supporting documents will be shared between both the University of Edinburgh and Glasgow.

For information on ‘How to Apply’ is detailed here:
Please note that all applications must be submitted via the University of Edinburgh:

Please note, you must apply to one of the projects and you must contact the primary supervisor prior to making your application. Additional information on the application process is available from the link above.

For more information about Precision Medicine visit:

Funding Notes

Start: September 2020

Qualifications criteria: Applicants applying for a MRC DTP in Precision Medicine studentship must have obtained, or will soon obtain, a first or upper-second class UK honours degree or equivalent non-UK qualification, in an appropriate science/technology area.

Residence criteria: The MRC DTP in Precision Medicine grant provides tuition fees and stipend of at least £15,009 (RCUK rate 2019/20) for UK and EU nationals that meet all required eligibility criteria.

Full eligibility details are available: View Website

Enquiries regarding programme:

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