MSc by Research programme - Development of tools suited for the in vivo identification and study of protein complexes in Phytophthora capsici, required for infection

Broad host range pathogens, such as the oomycete pathogen Phytophthora capsici, can cause significant disease on a wide range of plants. We have uncovered exciting new evidence demonstrating that P. capsici regulates the expression of its gene complement by sensing its host environment. In order to study the role of P. capsici proteins in dynamic host sensing however, there is a great need for tools that allow the study of both the transcriptional processes and the functional complexes underpinning their regulation, in this pathogen. In this project, we will pursue the following aims: 

1.  Devise an in vivo protein labelling technique, suited for the identification of functional protein complexes during infection 
2. Identify partners of candidate transcriptional regulators, important for virulence 
3. Validate and characterise protein complexes, required for infection of plants. 

During this project, the researcher will be trained in microbiology, protein chemistry, molecular biology as well as proteomics. Particular attention will be paid to the professional development of researchers on this project by providing career support and active mentoring. 

Please see our website for further details and how to apply -

Life Sciences MSc by Research MSc by Research (Postgraduate) : Study : University of Dundee