Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. We aim to understand the role of protein complexes including the exocyst in this pathway. This project seeks to answer mechanistic questions regarding 1) the regulation of protein structural mechanics in polarized trafficking, 2) and the consequences of signalling on this pathway and its organization. Because signalling in polarized trafficking is affected in metastasis of cancer, we position our research for the broadest impact in forming a foundation for drug discovery.
We take a reconstitution and synthetic biology approach in combination with the powerful tools available for microscopy and experimental cell biology, including methods such as stem cell biology and cryo electron microscopy. Our philosophy is to address questions of challenging biology using quantitative methods in a hypothesis-driven approach.
We are excited to introduce this interdisciplinary research to a highly motivated and ambitious student, who will be expected to have exemplary communication skills and an ability to collaborate. The student will emerge a master in state-of-the-art protein and cell biology approaches. For any questions on the nature of the proposed research, please to not hesitate to contact me directly [Email Address Removed] or by visiting our website.
https://sites.dundee.ac.uk/david-murray-lab/
Please see our website for further details on the programme:
Life Sciences MSc by Research MSc by Research (Postgraduate) : Study : University of Dundee
Please note before submitting your application that you must list your top three project choices in the Research Proposal section of the application form.
You apply for this course using our Direct Application System. Once you've signed up for an account you'll be asked to search for a course.
https://www.dundee.ac.uk/study/pgr/research-areas/life-sciences/
To find Life Science MSc by Research you should select the following options:
· Course type: Research Postgraduate
· Keyword: Life
When you complete your form, you should include your top 3 project choices, 2 letters of reference, uploaded under "Other Information" > "Supporting documents" and a personal statement. Failure to do so will delay your application.
Please note when submitting an application that we have the following deadline dates throughout the year:
September Starts - Application Deadline 1st May, Interview Date - Late June
January Starts - Application Deadline 1st Sep, Interview Date - Late October
May Starts - Application Deadline 1st Feb, Interview Date - Late March
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