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mTOR signalling: mechanisms of regulation in young and senescent cells (Newcastle)

This project is no longer listed on and may not be available.

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  • Full or part time
    Dr V Korolchuk
  • Application Deadline
    No more applications being accepted
  • Funded PhD Project (European/UK Students Only)
    Funded PhD Project (European/UK Students Only)

Project Description

The prospective student will be exposed to a thriving research environment working on an exciting project that aims to provide critical new insight into signal transduction pathways and their relevance to human ageing. The lead applicant’s lab is actively investigating mechanisms of mTOR signalling and the student will work alongside three experienced postdoctoral scientists thus benefitting from close supervision, mentoring and guidance. The student will be trained in state-of-the-art cell and molecular biological techniques, fluorescence and electron microscopic imaging, quantitative mass spectrometry and associated data analysis. Importantly, the student will gain competence in all aspects of sample handling and data-analysis for each of these techniques. Additionally, the prospective student will acquire essential transferable skills and will be expected to present at international conferences and publish in high profile scientific journals. Together, this training programme is an exceptional opportunity for a talented graduate to assemble a strong research portfolio and begin a successful career in life sciences.

For further information see the website:

To apply:
Please submit a full CV and covering letter directly to [Email Address Removed]

Funding Notes

This is a 4 year BBSRC studentship under the Newcastle-Liverpool-Durham DTP. The successful applicant will receive research costs, tuition fees and stipend (£14,057 for 2015-16). The PhD will start in September 2016. Applicants should have, or be expecting to receive, a 2.1 Hons degree (or equivalent) in a relevant subject. EU candidates must have been resident in the UK for 3 years in order to receive full support. There are 2 stages to the application process.


Korolchuk VI, Saiki S, Lichtenberg M, Siddiqi FH, Roberts EA, Imarisio S, Jahreiss L, Sarkar S, Futter M, Menzies FM, O'Kane CJ, Deretic V, Rubinsztein DC. (2011) Lysosomal positioning coordinates cellular nutrient responses. Nat Cell Biol. Apr;13(4):453-60.

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