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Multifunctional Biomaterials to Combat Infection and Modulate Inflammation


   School of Pharmacy

  , Prof Karl Malcolm, Dr Matthew Wylie  Applications accepted all year round  Competition Funded PhD Project (UK Students Only)

About the Project

Implantable medical devices are commonplace in modern medicine (e.g. joint replacements, stents, artificial heart valves, etc.), and are of ever increasing interest in the field of regenerative medicine. However, biomaterials from which such devices are made are essentially foreign to the human body, and are associated with triggering inflammation and immune reactions. Biomaterials are also a potential source of infection, owing to the ability of bacteria to attach and form biofilms on the material surface.

This project will focus on the quest for multifunctional biomaterials with combined properties that can combat infection, modulate inflammation, and promote regeneration at the same time. These properties are important considerations in the development of improved biomaterials for tissue scaffolds or implantable medical devices.

The cross-disciplinary project will provide an excellent opportunity for extensive training in a diverse range of scientific disciplines, including: polymer science, microbiology, advances analytical methods, medical device fabrication, cell culture, and molecular biology.

Applicants should have a 1st or 2.1 honours degree (or equivalent) in a relevant subject. Relevant subjects include Pharmacy, Pharmaceutical Sciences, Biochemistry, Biological/Biomedical Sciences, Chemistry, Engineering, or a closely related discipline. Students who have a 2.2 honours degree and a Master’s degree may also be considered, but the School reserves the right to shortlist for interview only those applicants who have demonstrated high academic attainment to date.

PhD programmes at Queen’s University Belfast are intended from the outset to include extensive training in modern research methods, and students are encouraged to make good use of the many excellent courses run by the QUB Graduate School. This project will help the student develop the key skills and knowledge that will make them highly attractive for employment in the medical devices industry. The student will be trained in a multidisciplinary environment and follow a personal development plan (PDP).

The student will be provided with the opportunity to disseminate their work through high quality journal outputs, and by participation at national and international conferences.

The project will further develop the knowledge and understanding of in research area, translating in the development of innovative biomaterials that ultimately improve healthcare outcomes.

Applicants should apply through the University's Direct Application Portal: https://dap.qub.ac.uk/portal/user/u_login.php


Funding Notes

Department for the Economy studentships are available for eligible UK and Irish residents. This is a three year studentship beginning on 2nd October 2023, the deadline for applications is the 30th January 2023. The successful candidate will receive a stipend and have their tuition fees paid for. For more details, please see the following link: View Website

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