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  Multifunctional Biomaterials to Combat Infection and Modulate Inflammation

   School of Pharmacy

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  Dr Louise Carson, Prof Karl Malcolm, Dr Matthew Wylie  Applications accepted all year round  Self-Funded PhD Students Only

About the Project

Implantable medical devices are commonplace in modern medicine (e.g. joint replacements, stents, artificial heart valves, etc.), and are of ever increasing interest in the field of regenerative medicine. However, biomaterials from which such devices are made are essentially foreign to the human body and can trigger inflammation and immune reactions. Biomaterials are also a potential source of infection, as bacteria can attach and form biofilms on the material surface.

This project will focus on the quest for multifunctional biomaterials with properties that can simultaneously combat infection, modulate inflammation, and promote regeneration. These properties are important considerations in the development of improved biomaterials for tissue scaffolds or implantable medical devices.

The cross-disciplinary project will provide an excellent opportunity for extensive training in a diverse range of scientific disciplines, including: polymer science, microbiology, advances analytical methods, medical device fabrication, cell culture, and molecular biology.

PhD programmes at Queen’s University Belfast are intended from the outset to include extensive training in modern research methods, and students are encouraged to make good use of the many excellent courses run by the QUB Graduate School. This project will help the student develop the key skills and knowledge that will make them highly attractive for employment in the medical devices industry. The student will be trained in a multidisciplinary environment and follow a personal development plan (PDP).

The student will be provided with the opportunity to disseminate their work through high quality journal outputs, and by participation at national and international conferences.

The project will further develop the knowledge and understanding of in research area, translating in the development of innovative biomaterials that ultimately improve healthcare outcomes.

Home applicants must meet the following academic criteria:

1st or 2.1 honours degree in a relevant subject. Relevant subjects include Pharmacy, Pharmaceutical Sciences, Biochemistry, Biological/Biomedical Sciences, Chemistry, Engineering, or a closely related discipline.

International applicants must meet the following academic criteria:

IELTS (or equivalent) of 7.0, a 2.1 honours degree (or equivalent) and a master’s degree in a relevant subject.

Applicants should apply through the University's Direct Application Portal:

Biological Sciences (4) Engineering (12) Medicine (26)

 About the Project