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Multistep Phosphorelay Signaling in Crop Stress

  • Full or part time
  • Application Deadline
    Sunday, February 03, 2019
  • Competition Funded PhD Project (Students Worldwide)
    Competition Funded PhD Project (Students Worldwide)

Project Description

In our lab we are interested in the study of plant hormonal signaling pathways, particularly cytokinins (CKs) in the development of model plant Arabidopsis thaliana (1-4). more details see here. Published evidence suggest importance of cytokinins in the abiotic stress response (5). In our previous work, we have identified cytokinin receptors in Brassica napus (oil-seed rape) (6). The goal of the thesis is to determine i) missing members of multistep phosphorelay (MSP) pathway in oil-seed rape, ii) describe natural variability in the individual members of the MSP signaling both in Arabidopsis and oil-seed rape , iii) identify the role of individual variants in the MSP signal transduction and draught response and iv) improve crop drought resistence via CRISPR-Cas9 targeted genome editing. The work will include applying bioinformatics, molecular biology, genomics, advanced microscopy and phenotyping approaches. Phenotyping will be performed in a collaboration with Photon Systems Instruments, Ltd. employing their PlantScreenTM phenotyping platform.
We offer:
Experimental work on own project with the possibility of publication in top-ranked international journals
Friendly lab staff, world-class equipment, attractive environment of novel university campus, help with both intellectual and practical problems
Competitive salary corresponding to the work efficiency
We expect:
Excellent Master degree in Chemistry, Biochemistry, Molecular Biology, or related fields; own publication record is advantageous
High motivation to perform creative basic Research
Candidates should be team players, have good communication skills and good knowledge of the English language

Applicants who wish to pursue a degree at the CEITEC PhD programme must hold the equivalent of a Master’s degree (MSc) in similar field (four or five year undergraduate degree). The application can be submitted before obtaining the Master’s degree, however, the applicant should obtain the degree within five month after the application deadline.

All general enquiries should be directed to Olga Krizova (). Scientific inquiries can be addressed to the supervisor ().

Funding Notes

Admission for studies, student registration for the full-time study programme and proper fulfilment of student duties constitute the student’s right to a regular scholarship of 22 000 CZK (850 EUR). Information is available at View Website

Living costs and other practicalities available at View Website


1. Dobisova, T., et al. (2017). Plant Physiol 174, 387-404.
2. Paniagua, C., et al. (2017). J Exp Bot.
3. Pernisova, M., et al. (2016). New Phytol 212, 497-509.
4. Pernisova, M., et al. (2018). Development.
5. Zwack, P. J., et al. (2015). Journal of Experimental Botany.
6. Kuderova, A., et al. (2015). Journal of Experimental Botany 66, 339-353.

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