About the Project
The aim of this project will be to determine the activity of nanoparticle encapsulated antibiotics against a wide range of pathogens detected in the lung microbiome. In vitro activity will be determined using planktonic and biofilm models of infection under aerobic and anaerobic conditions, similar to those found in sputum in the lungs of CF patients. In vivo activity will be determined using sputum from patients with lung infection. Depending on results, further formulation studies may be undertaken to optimize antimicrobial activity. Extensive training will be provided throughout the project as part of internationally renowned research teams
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