£6,000 FindAPhD Scholarship | APPLICATIONS CLOSING SOON! £6,000 FindAPhD Scholarship | APPLICATIONS CLOSING SOON!

New anticancer therapies based on transition metal complexes


   Department of Chemistry

  Prof Jim A Thomas  Applications accepted all year round  Self-Funded PhD Students Only

About the Project

Cancer is one of the leading causes of death around the world. Over 50% of cancer tumours are treated with platinum-based metal complexes, like cisplatin and its derivatives. While these chemotherapeutics have been hugely successful, many forms of cancer are intrinsically resistant to the chemotherapeutics and others can rapidly acquire resistance to these treatments. We have identified new ruthenium-based metal complexes that are promising leads for cancer treatment. Because they work in a very different way to platinum-based drugs they are active in resistant cancer cells such as cisplatin-resistant ovarian cancer. See this press release for more details:

https://www.sheffield.ac.uk/news/nr/new-compound-could-help-treat-ovarian-cancer-1.831678

In this multidisciplinary project you will gain experience - and be trained in - organic and inorganic synthesis, and a range of cell biology skills, including various forms of state-of-the-art microscopy.

All applications must be submitted via the online application portal:

https://www.sheffield.ac.uk/postgradapplication/


Funding Notes

This is a self-funded project. You should have or expect to gain at least an upper second-class MChem or Masters degree, or equivalent, in a relevant subject.
If you have the correct qualifications and access to your own funding, either from your home country or your own finances, your application to work with this supervisor will be considered.
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