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New insights into rumen acidosis from the volatile metabolome measured using SIFT mass spectrometry

  • Full or part time
  • Application Deadline
    Sunday, March 03, 2019
  • Funded PhD Project (European/UK Students Only)
    Funded PhD Project (European/UK Students Only)

Project Description

This project will use new selected-ion flow-tube mass spectrometry (SIFT-MS) equipment to provide a detailed analysis of cow breath and use it to explore mechanisms associated with sub-acute rumen acidosis (SARA). The student will use a series of in vitro rumen incubations and in vivo studies to explore factors affecting the release of volatile organic compounds that may be involved in the aetiology of SARA. The initial focus will be on volatile amines produced by fermentation of amino acids under low pH conditions, though comprehensive analysis of gas samples using SIFT-MS may allow us to study novel pathways.

The student will be registered for the degree of PhD at the University of Glasgow and will need to meet their entry requirements as a minimum. We expect candidates to have experience of ruminant nutrition and production, with evidence of an aptitude for work with farm livestock, analytical instruments, data handling and analysis, as well as written and oral presentations.

The studentship will commence 1st October 2019, with work being conducted at SRUC campuses at Easter Bush (Edinburgh) and Dumfries (Dairy Centre). The student will also have the opportunity to work with collaborators using GC-MS at the INRA research centre in Clermont-Ferrand.

Funding Notes

The stipend will be set at UKRI recommended levels for a 3.5 year-period and the studentship is funded to pay domestic tuition fee levels for UK/EU students. The student will receive an annual student stipend of £14,777 (£15,009 in 2019/20). This studentship will fund to pay the tuition fees at home fees rate only. International students must provide evidence of sufficient funds to cover the higher international student tuition fee level (approximately £16,740 per year would be required).

How good is research at SRUC - Scotland’s Rural College in Agriculture, Veterinary and Food Science?
(joint submission with University of Edinburgh)

FTE Category A staff submitted: 57.37

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

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