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New strategies for treatment of diabetic kidney disease


Project Description

This project is one of 9 four-year PhD Studentships funded by Medical Research Scotland (http://www.medicalresearchscotland.org.uk) to be delivered jointly by the named University and Company. The Studentship will provide the first-class academic and commercial training needed to equip the successful candidate for a science career in an increasingly competitive market.

"Potential new strategies for the treatment of kidney disease due to diabetes" to be delivered by the University of Aberdeen [Supervisors: Professor Mirela Delibegovic and Dr Heather Wilson (both School of Medicine, Medical Sciences and Nutrition)] and MedImmune Ltd (https://www.medimmune.com/) [Company supervisor: Dr David Baker].

Type-1 and type-2 diabetes are both characterised by poor blood glucose level control. This is associated with increased glucose production from the liver which ultimately leads to other complications including progressive loss of kidney function due to podocyte damage. Diabetic kidney disease, also known as diabetic nephropathy remains one of the leading causes of reduced lifespan in diabetes and is the leading cause of end-stage kidney disease, where dialysis and transplantation are the only options for survival. Consequently, there is a great unmet need for treatments to reduce diabetic nephropathy development and progression. In this project we aim to test new ways of treating diabetic kidney disease using a range of in vitro and in vivo techniques and novel drugs.

ENQUIRIES:

Enquiries should be sent by email to Professor Mirela Delibegovic:


APPLICATIONS:
Applicants must have obtained, or expect to obtain, a first or 2.1 UK honours degree, or equivalent for degrees obtained outside the UK, in Biochemistry, Physiology, Pharmacology or Neuroscience. MRes/MSc would be desirable.

Please select ’Degree of Doctor of Philosophy in Medical Sciences’ from the list of programme options in the University of Aberdeen postgraduate applicant portal (https://www.abdn.ac.uk/pgap/login.php), then enter the name of the funder (Medical Research Scotland), name of supervisor(s) and project title in the space provided. A research proposal is not required when applying for an advertised PhD studentship.

When submitting your online application, please also provide a CV, the contact details of 2 academic references (including email addresses) and a covering letter, explaining why you wish to carry out this project.

Please note, your application may be shared with the funders of this PhD Studentship, Medical Research Scotland and MedImmune Ltd.

Interviews are expected to take place 3-4 weeks after the closing date.

It is anticipated that the PhD Studentship will start in October 2019.

Funding Notes

PhD Studentship provides: an annual tax-free stipend of £17,500, increasing to £18,000 over the four years; tuition fees at UK/EU rates only; consumables; and contribution to travel expenses. International fees are not covered.

References

https://www.abdn.ac.uk/ims/profiles/m.delibegovic

How good is research at Aberdeen University in Biological Sciences?

FTE Category A staff submitted: 89.42

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

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