This is a 4 year BBSRC studentship under the Newcastle-Liverpool-Durham DTP. The successful applicant will receive research costs, tuition fees and stipend (£15,009 for 2019-20). The PhD will start in October 2020. Applicants should have, or be expecting to receive, a 2.1 Hons degree (or equivalent) in a relevant subject. EU candidates must have been resident in the UK for 3 years in order to receive full support. Please note, there are 2 stages to the application process.
High-speed imaging of glutamate release with genetically encoded sensors. Nature Protocols. 2019 May;14(5):1401-1424. doi:
Single Synapse Indicators of Impaired Glutamate Clearance Derived from Fast iGlu u Imaging of
Cortical Afferents in the Striatum of Normal and Huntington (Q175) Mice. Journal of
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Ultrafast glutamate sensors resolve high-frequency release at Schaffer collateral synapses. PNAS. 2018 May 22;115(21):5594-5599. doi: 10.1073/pnas.1720648115.
Design and mechanistic insight into ultrafast calcium indicators for monitoring intracellular calcium dynamics. Scientific Reports. 2016 Dec 6;6:38276. doi: 10.1038/srep38276.
Fast-Response Calmodulin-Based Fluorescent Indicators Reveal Rapid Intracellular Calcium Dynamics. Scientific Reports. 2015 Nov 3;5:15978. doi:10.1038/srep15978.
A novel fluorescent sensor protein for detecting changes in airway surface liquid glucose concentration. Biochemical Journal. 2014 Dec 1;464(2):213-20. doi: 10.1042/BJ20141041.
Transport and self-organization across different length scales powered by motor proteins and programmed by DNA. Nature Nanotechnology, 2014, 9(1), 44–47.
Characterising Maturation of GFP and mCherry of Genomically Integrated Fusions in Saccharomyces cerevisiae. Bio-protocol, 2018, 8(2).
Transcription factor clusters regulate genes in eukaryotic cells. ELife, 2017, 6, e27451.
Staphylococcus aureus toxin LukSF dissociates from its membrane receptor target to enable renewed ligand sequestration. The FASEB Journal, 2018, fj.201801910R-fj.201801910R