Next generation modelling for the pharmaceutical industry

We have an outstanding opportunity to make an impact in pharmaceutical manufacturing research, by conducting innovative modelling of particulate processes for the pharmaceutical industry.

In the research project, we aim to create models for powder-based pharmaceutical manufacturing, using both data driven and mechanistic modelling approaches. Processes of interest include filtration and drying, wet granulation, spherical agglomeration, blending and tabletting. As the researcher, you will join the EPSRC MediForge: Industry 5.0 Medicines Manufacturing Research Hub, a consortium of 4 Universities and 19 companies. 

Professor Rachel Smith and her research group at the University of Sheffield are world leaders in particle and pharmaceutical product design and formulation. The group is well known for their work in wet granulation. They also work in roll compaction, spray drying, fluidized bed processes, spherical agglomeration, crystallization, and modelling of product performance. Research in the group is a mixture of experimental and computation work. A current key focus of the group is development of new multiscale modelling approaches, coupled with data driven modelling techniques, to support predictive, process and product engineering.

Modelling tools to be used will vary according to the application but are likely to including process simulation using Population Balance Modelling, DEM simulations and Machine Learning Approaches.

You will have access to the excellent training opportunities at the University of Sheffield. A range of highly desirable skills will be learnt through this project. In particular, you will gain training in computational methods. You will also gain experience in pharmaceutical characterisation and manufacturing techniques, particle size and shape analysis, research methodology, professional writing, and oral presentations. Expert training in specific tools will be provided to the successful candidate.

Entry Requirements:

A successful applicant would have a first or upper second class degree in Chemical Engineering, Pharmaceutical Engineering, Materials Engineering, Mechanical Engineering, the Physical Sciences such as Physics or Chemistry, Materials Science, or other related discipline.

Please see this link for information on how to apply: https://www.sheffield.ac.uk/cbe/postgraduate/phd/how-apply. Please include the name of your proposed supervisor and the title of the PhD project within your application.