Information on this PhD research area can be found further down this page under the details about the Widening Participation Scholarship given immediately below.
Applications for this PhD research are welcomed from anyone worldwide but there is an opportunity for UK candidates (or eligible for UK fees) to apply for a widening participation scholarship.
Widening Participation Scholarship: Any UK candidates (or eligible for UK fees) is invited to apply. Our scholarships seek to increase participation from groups currently under-represented within research. A priority will be given to students that meet the widening participation criteria and to graduates of the University of Salford. For more information about widening participation, follow this link: https://www.salford.ac.uk/postgraduate-research/fees. [Scroll down the page until you reach the heading “PhD widening participation scholarships”.] Please note: we accept applications all year but the deadline for applying for the widening participation scholarships in 2024 is 28th March 2024. All candidates who wish to apply for the MPhil or PhD widening participation scholarship will first need to apply for and be accepted onto a research degree programme. As long as you have submitted your completed application for September/October 2024 intake by 28 February 2024 and you qualify for UK fees, you will be sent a very short scholarship application. This form must be returned by 28 March 2024. Applications received after this date must either wait until the next round or opt for the self-funded PhD route.
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Project description: Cancer nanotechnology1 is an exciting field of research which aims to involve the use of engineered nanomaterials for the diagnosis, treatment, and prevention of cancer. Key use of nanotechnologies focuses on the improvement of commonly occurring side effects observed in traditional cancer therapies, in particular radiotherapy where nanoparticles play a key role in radiation dose enhancement2 and chemotherapy, where the drug dosing can be improved in synergy with the custom functionalised engineered nanoparticles.
To advance this field, we have recently generated a new type of engineered nanoparticle which is due to be developed further in view of designing a new nuclear nanomedicine. We are offering a three-year PhD interdisciplinary project for self-funded students only, which will be supervised by Dr Zeljka Krpetic (University of Salford). The project aims at optimising new wet-chemistry approaches to the synthesis of the high-quality nanoparticles, with wide range of sizes providing robust outputs on the particle characterisation via the state-of-the-art analytical methods (e.g. Dynamic Light Scattering (DLS), Differential Centrifugal Sedimentation (DCS)3, Nanoparticle Tracking Analysis (NTA), Scanning Electron Microscopy (SEM)), including the analysis of the biomolecular coronas4 and in vitro study of the cell viability including a variety of relevant cell lines. This part of the project will be developed over two years at the Bionanotechnology laboratory at the University of Salford (www.zknanolab.com). This project also involves an additional opportunity of exploring the radiation-induced synthesis. The PhD candidate will regularly visit Dalton Cumbrian Facility (DCF), a specialist radiation science laboratory run by a Higher Education Institute at The University of Manchester where the radiation-induced synthesis of the target nanomaterials will be further explored in view of delivering novel nuclear nanomedicine systems suitable for theranostic applications in collaboration with Dr Aliaksandr Baidak and Professor Frederick Currell (University of Manchester).
For any enquiries, please contact Dr Zeljka Krpetic (Z.Krpetic@salford.ac.uk)
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