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Novel applications of liquid MALDI MS for the analysis of large biomolecules


Project Description

This PhD project will investigate novel applications of liquid MALDI MS in the areas of hydrogen/deuterium exchange for structural biology, native mass spectrometry, top-down biomolecule analyses and enzyme assay and kinetics measurements. In addition, further optimisation of the liquid MADLI ion source and its off-line coupling to other preparative techniques will be investigated with the objective to find the ultimate speed for entire workflows as needed in omics analyses or (bio)assaying. The project is partly funded by our industrial collaborator Waters Corporation.

To apply for this studentship please submit an application for a PhD in Chemistry at http://www.reading.ac.uk/graduateschool/prospectivestudents/gs-how-to-apply.aspx
*Important note*
1) Please quote the reference ‘GS20-012’ in the ‘Scholarships applied for’ box which appears within the Funding Section of your on-line application.
2) When you are prompted to upload a research proposal, please omit this step.

Funding Notes

• Applicants should hold or expect to gain a minimum of a 2:1 Bachelor Degree or equivalent in the Physical or Life Sciences.
• Due to restrictions on the funding this studentship is open to UK/EU students.

• Tuition fees plus stipend

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