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  Novel liquid crystalline depots for controlled drug delivery (QIS2U20JANS)


   School of Pharmacy

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  Dr S Qi  No more applications being accepted  Funded PhD Project (European/UK Students Only)

About the Project

Liquid crystalline materials have been widely explored for applications in drug delivery [1-3]. The biggest challenge in this field of research is controlling the formation of the liquid crystalline structure and using this structure to manipulate drug delivery to optimise therapeutic outcomes. This is a fully funded PhD studentship in cooperation with Janssen. In this PhD project, you will engineer a range of novel materials composed of liquid crystalline structures. These materials will be used to carry drugs and provide slow and controlled drug delivery after being injected or implanted in the body. The successful student will work in the state-of-the-art drug delivery lab at the School of Pharmacy and receive excellent training on advanced materials sciences research and transferable skills to ensure they can build a successful career beyond their PhD. The project is a close research collaboration with Janssen. The student will have a fixed period of exchange embedded within the Janssen’s R&D team and gain insights into industrial research and product development.

For more information on the supervisor for this project, please go here: https://people.uea.ac.uk/sheng_qi

This is a PhD programme.

The start date of the project is 1 December 2020.

The mode of study is full-time. The studentship length is 3 years. Please note, 3-year studentships have a (non-funded) 1-year ‘registration only’ period.


Funding Notes

This PhD studentship is funded for 3 years by Janssen Research and Development. Funding is available to UK/EU applicants only and includes Home/EU tuition fees an annual stipend of £15,459 in year 1, rising to £16,400 in year 3.

Entry requirements

Acceptable first degree in Pharmacy, Pharmaceutical Sciences, Materials Sciences, Biomedical Engineering, Chemical Engineering and other relevant subject areas.

The standard minimum entry requirement is 2:1.

References

i) Controlling molecular transport and sustained drug release in lipid-based liquid crystalline mesophases. J Control Release. 2014;188:31-43

ii) Bicontinuous cubic liquid crystals as sustained delivery systems for peptides and proteins. Expert Opin Drug Deliv. 2010 Oct;7(10):1133-44

iii) Controlling release from the lipidic cubic phase. Amino acids, peptides, proteins and nucleic acids. J Control Release. 2005;107(1):97-111.

Where will I study?