Technological advances in the fields of microfluidics and tissue engineering have enabled the establishment of biomimetic lab-on-a-chip systems that resemble human biology at the cellular, tissue and organ levels. These organs-on-a-chip platforms offer the exciting potential to enable screening and testing of drugs without the needs for animal or human testing. In this project we aim to develop a novel microfluidic platform that mimics the function and biology of the gut with a view to developing a new generation of therapeutics that are delivered orally. These novel therapeutics will be delivered using artificial cells that hijack transport systems within the body. This is a highly exciting project that couples blue skies and applied research and will provide the successful applicant with a wealth of experience in microfluidics, artificial cell technologies, drug delivery and microscopy.