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This PhD project is offered on a self-funding basis. It is open to applicants with funding or those applying to funding sources. Details of tuition fees can be found at http://www.uea.ac.uk/pgresearch/pgrfees.
A bench fee is also payable on top of the tuition fee to cover specialist equipment or laboratory costs required for the research. The amount charged annually will vary considerably depending on the nature of the project and applicants should contact the primary supervisor for further information about the fee associated with the project.
i) Helliwell RM, ShioukHuey C O, Dhuna K, Molero JC, Ye J-M, Xue CC, Stokes L. Selected ginsenosides of the protopanaxdiol series are novel positive allosteric modulators of P2X7 receptors. British Journal of Pharmacology 2015 172(13):3326-40. doi 10.1111/bph.13123
ii) Bartlett R, Stokes L, Sluyter R The P2X7 purinergic receptor: recent developments and the use of P2X7 antagonists in models of disease. Pharmacological Reviews. 2014 66(3):638-75. doi: 10.1124/pr.113.008003.
iii) Stokes L, Fuller SJ, Sluyter R, Skarratt KK, Gu B, Wiley JS. Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1 secretion. FASEB Journal. 2010 24(8): 2916-27.