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Novel techniques in molecular metabolism


Project Description

The successful applicants will be joining an internationally-renowned research group, within one of the world’s top research universities. The department has an excellent publication record in top rated research journals and is well funded from a number of different sources, including grants recently awarded by the Wellcome Trust, the MRC and the BBSRC.

Project
We have recently invented an exciting new in vivo imaging technique to monitor metabolic health in mouse models of obesity and insulin resistance. The successful candidate will learn the new technique, demonstrate its utility, and use it to make discoveries in the fields of metabolic health and tumour growth.

Training
Full training will be given in all applicable techniques. These include intravital imaging, the use of genetically modified mice, in vitro genetic modification of organoids, and laboratory molecular techniques. The candidate will also receive training in experimental planning, data interpretation, statistical analysis, manuscript preparation, and scientific communication at major national and international conferences. These transferable skills will ensure that the candidate is in an ideal position to progress on to a successful career in academic or industrial science.

Host lab
The project will be supervised by Dr Bryn Owen and Dr Victoria Salem in the Section of Investigative Medicine. Together they currently co-supervise seven PhD students, and have a broad expertise in models of metabolic disease.

The student will be based on the Hammersmith campus.

Applicants must have a first or upper second class degree from a UK University or the overseas equivalent in a relevant area of biochemistry, physiology, or neuroscience. In addition a Masters degree is preferable but not essential. Experience in molecular biology and in vivo physiology is a major advantage. Applicants must also meet Imperial College’s English language requirements – further details can be found at http://www3.imperial.ac.uk/registry/admissions/pgenglish. Finally, applicants must be prepared to work under the Animals (Scientific Procedures) Act 1983.

Funding Notes

Applicants must have a first or upper second class degree from a UK University or the overseas equivalent in a relevant area of biochemistry, physiology, or neuroscience. In addition a Masters degree is preferable but not essential. Experience in molecular biology and in vivo physiology is a major advantage. Applicants must also meet Imperial College’s English language requirements – further details can be found at View Website. Finally, applicants must be prepared to work under the Animals (Scientific Procedures) Act 1983.

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