Novel Therapies targeting Cardiovascular Disease. Synthetic Lipoxin-A4 mimetics: novel therapeutic approaches to target residual inflammatory risk in Atherosclerosis-Associated Diabetes Complications.

Atherosclerosis is a life-long condition essentially due to an inflammatory reaction that drives accumulation of fats and cell debris into the vessel wall, blocking the blood flow. Diabetes accelerates this process. In this context, the role of substances naturally produced by our body to turn-off inflammation has emerged. However, their use as drugs is limited, due to their rapid breakdown in the body. Therefore, longer-lasting molecules have been created and their protective action against developing diabetic atherosclerosis will be tested in this project. For full details of the project and how to apply see here.