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Now where was I? The changing role of prefrontal and motor cortices as a function of healthy ageing

  • Full or part time
  • Application Deadline
    Friday, April 12, 2019
  • Funded PhD Project (Students Worldwide)
    Funded PhD Project (Students Worldwide)

Project Description

The overall aim of the project is to advance knowledge of normal human function in a task that requires sensorimotor processes common to those of everyday activities such as driving.

Objective 1 and 2: Investigate ocular behaviour, and functioning of the pre-frontal (DLPFC) and motor cortex, during dual-task remembered pursuit protocol; Investigate the contribution from motor efference and/or movement-elicited afference during dual-task remembered pursuit.

Hypotheses: i) Ability to relocate the eyes on the pursuit object will be improved when there is concurrent wrist motion; ii) Measures of ocular pursuit will be influenced by the demands of a secondary task, but less so during oculo-manual pursuit; iii) ΔHbO and ΔHbR in M1 will differ between conditions of ocular and oculo-manual pursuit, and will be increase in DLPFC while completing dual-task pursuit compared to control conditions.

Objective 3 and 4: Investigate factors that influence the functional state of the extensor carpi radialis representation in M1 during dual-task pursuit; Investigate the consequence of a temporary central perturbation to the ECR representation in M1 or DLPFC on the ocular response.

Hypotheses: i) Increase in excitability of M1 while completing the secondary task; ii) Excitability of the motor system related temporally to completion of the secondary task; iii) Contribution of movement-elicited afference and motor efference related to the functional state of M1.

Applications

Applicants must apply using the online form on the University Alliance website at https://unialliance.ac.uk/dta/cofund/how-to-apply-2/. Full details of the programme, eligibility details and a list of available research projects can be seen at https://unialliance.ac.uk/dta/cofund/

The final deadline for application is 12 April 2019.

Funding Notes

DTA3/COFUND participants will be employed for 36 months with a minimum salary of (approximately) £20,989 per annum. Tuition fees will waived for DTA3/COFUND participants who will also be able to access an annual DTA elective bursary to enable attendance at DTA training events and interact with colleagues across the Doctoral Training Alliance(s).
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 801604.

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