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Optimising pharmacological treatment of non-cognitive symptoms in people with dementia


School of Pharmacy

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Dr H Barry , Prof C Hughes Applications accepted all year round Self-Funded PhD Students Only

About the Project

Non-cognitive symptoms experienced by people with dementia may include agitation, aggression, distress, psychosis, anxiety and depression. The management of non-cognitive symptoms in people with dementia is often challenging and if left untreated, such symptoms can accelerate decline, reduce quality of life, and cause substantial distress to both patients and carers. Often non-pharmacological management options are recommended first-line, but pharmacological management may need to be considered if the patient does not respond to non-pharmacological approaches. However, some pharmacological treatments need to be prescribed with caution and evaluated regularly. This mixed-methods project will investigate current prescribing of pharmacological treatments for non-cognitive symptoms in people with dementia and explore the experiences of key stakeholders (such as people with dementia, their carers, relevant healthcare professionals), in order to assess how prevention and treatment of non-cognitive symptoms may be improved and optimised for this patient population.

Funding Notes

Applicants should have a 1st or 2.1 honours degree (or equivalent) in a relevant subject. Relevant subjects include Pharmacy, Molecular Biology, Pharmaceutical Sciences, Biochemistry, Biological/Biomedical Sciences, Chemistry, Engineering, or a closely related discipline. Students who have a 2.2 honours degree and a Master’s degree may also be considered, but the School reserves the right to shortlist for interview only those applicants who have demonstrated high academic attainment to date


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