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Personalized management of blood testing for renal function in patients with and without diabetes


College of Medicine, Veterinary and Life Sciences

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Dr P Welsh , Dr P Mark No more applications being accepted Competition Funded PhD Project (Students Worldwide)

About the Project

Supervisors:
Dr Paul Welsh
Prof Patrick Mark
Prof Juan-Jesus Carrero

Project summary:
Testing of renal function using blood and urine samples is a key method of monitoring health of patients with diabetes and is recommended every year. Renal function is also tested ad hoc in people without diabetes. However, the evidence base to support either of these approaches is weak and may well result in unnecessary cost burdens to the NHS and/or missing people who may benefit additional screening. Using Scotland’s world class health informatics, we propose a data science approach encapsulating routinely collected health data in NHS Greater Glasgow and Clyde, with 1.2M registered patients, to develop an evidence-based algorithm for personalized renal function testing. The project will provide a holistic overview of who is currently getting renal function tested in practice, and what the optimal approaches for the future would look like. We will perform parallel external validation studies in a similar healthcare extraction from the region of Stockholm, Sweden, allowing collaboration for the student with recognized International experts. This transformative approach has the potential to influence future clinical guidelines. The student will gain exposures to key quantitative skills and well as developing clinical insights and experience in data synthesis from review of clinical guidelines.

This MRC programme is joint between the Universities of Edinburgh and Glasgow. You will be registered at the host institution of the primary supervisor detailed in your project selection.

All applications should be made via the University of Edinburgh, irrespective of project location via the link below.

http://www.ed.ac.uk/studying/postgraduate/degrees/index.php?r=site/view&id=919

Please note, you must apply to one of the projects and you must contact the primary supervisor prior to making your application. Additional information on the application process is available from the link above.

For more information about Precision Medicine and what is required when submitting an application, please visit:
https://www.gla.ac.uk/colleges/mvls/graduateschool/mrcdtpprecisionmedicine/


Funding Notes

Start: September 2021

Qualifications criteria: Applicants applying for an MRC DTP in Precision Medicine studentship must have obtained, or will soon obtain, a first or upper-second class UK honours degree or equivalent non-UK qualification, in an appropriate science/technology area. The MRC DTP in Precision Medicine grant provides tuition fees and stipend of at least £15,285 (UKRI rate 2020/21).

Full eligibility details are available: http://www.mrc.ac.uk/skills-careers/studentships/studentship-guidance/student-eligibility-requirements/

Enquiries regarding programme: [Email Address Removed]

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