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PhD in Biomedical Engineering: High-throughput Microfluidic Droplet Sorting for Industrial Applications

  • Full or part time
  • Application Deadline
    Sunday, June 30, 2019
  • Competition Funded PhD Project (European/UK Students Only)
    Competition Funded PhD Project (European/UK Students Only)

Project Description

A graduate studentship leading to the award of a PhD is available to work at the University of Glasgow in the School of Engineering, with Prof. Thomas Franke. The project will be completed in collaboration with our industrial partner and visits to their sites are required.

This project will involve the setup and optimization of high-throughput microfluidic droplet sorting systems, plus the testing of the suitability of such systems (in terms of sorting rate and detection sensitivity) for different industrially relevant applications.

This includes but is not limited to the following tests:

- Determining sensitivity of the sorter using different fluorescence detection methods. For example, one target will be to determine the sensitivity of the sorter, relative to rate of sorting, using a biochemical fluorescence assay.
- Other work will involve the use of commercially available E. coli containing incorporated green fluorescent protein (GFP). The target will be to determine the sensitivity relative to number of cells expressing GFP per droplet.
- Experiments will be performed with two different metabolite producing bacteria strains, where the metabolite can be identified using a fluorescence detection method. The target is to successfully identify and sort best 1 – 5% producers.

Applicants should have a university degree in physics, engineering, biotechnology, chemistry or a related, relevant subject. Specific skills in microfluidics, directed evolution, lab on a chip technology, chemical and kinetic analysis of enzyme mechanisms, proteomics, cell sorting and cytometer technology, integrations and automatization of microfluidics are highly advantageous.

Please direct informal enquiries to .

Funding Notes

The studentship is supported by the University and an industry partner and it will cover tuition fees and provide a stipend of £15,009 (subject to annual increments) for 3.5 years for home/EU students.

How good is research at University of Glasgow in General Engineering?

FTE Category A staff submitted: 84.00

Research output data provided by the Research Excellence Framework (REF)

Click here to see the results for all UK universities

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